S-Acetyl L-Glutathione 300mg Capsules

The acetylated form of your body's master antioxidant, 300 mg per capsule.* MaxLife S-Acetyl L-Glutathione delivers glutathione with a protective acetyl group, in an acid-resistant capsule built to get through the stomach.

• Acetylated for stability. The acetyl group protects glutathione so more of it can reach your cells intact.*
• Studied in humans. In a randomized crossover study, S-acetyl glutathione raised plasma glutathione higher than standard glutathione.*†
• 300 mg per capsule. The right dose, not the biggest number.
• Acid-resistant capsule. Built to get through the stomach.
• 60-day money-back guarantee. Even if opened.

Key facts

Who it's for

Adults who want daily antioxidant support as part of a longevity routine, especially people who train hard, travel often, sleep less than they'd like or simply want to support their body's own glutathione as they get older.*

Why glutathione

Glutathione is the antioxidant your cells make themselves. It helps neutralize free radicals, recycles other antioxidants like vitamins C and E, and supports your body's natural detoxification processes.* Everyday stressors — intense training, poor sleep, alcohol, pollution and simply getting older — all draw on your supply.

Why the S-acetyl form

Standard glutathione is fragile. It breaks down quickly in the digestive tract and bloodstream, which is why its absorption has been debated for decades.

S-acetyl glutathione adds a small acetyl group to the glutathione molecule. That group acts as a shield: it keeps the molecule more stable in the blood and lets cells take it up directly. Once inside, the cell removes the acetyl group and releases active glutathione where it's needed.*

S-acetyl vs. other forms of glutathione

What the research shows

The S-acetyl form, head to head. In a randomized crossover study of healthy adults, researchers gave volunteers a single oral dose of S-acetyl glutathione and, on a separate occasion, the same amount of standard glutathione. S-acetyl glutathione produced a higher peak and greater total plasma glutathione than standard glutathione, and was well tolerated.*† (Fanelli et al., 2018)

Why daily use matters. A 6-month randomized, double-blind, placebo-controlled trial of standard oral glutathione in 54 adults found that body glutathione stores rose over months of daily use — by 30–35% in blood components at 1,000 mg/day — and returned to baseline within a month of stopping.* (Richie et al., 2015) The takeaway: glutathione support works through consistency, not a one-off dose.

† The S-acetyl study used a single 3.5 g dose in 17 participants. MaxLife provides 300 mg per capsule for daily use. The 6-month trial used standard reduced glutathione, not the S-acetyl form.

How to take it

Take as directed on the label. For best results, take it every day — glutathione support builds with consistent use. Part of the Renewal Protocol alongside Liposomal NAD+ and NMN.

FAQ

What is S-acetyl glutathione?
It's glutathione with a protective acetyl group attached. The group helps it stay stable in the blood and enter cells, where it's converted back into active glutathione.*

Is S-acetyl glutathione better than liposomal glutathione?
They protect glutathione in different ways. Liposomal wraps it in a fat bubble, usually as a liquid or softgel. S-acetyl protects the molecule itself, so it fits in a simple capsule. Both have human research behind them; S-acetyl is the choice if you want an easy daily capsule.*

Is 300 mg enough?
We chose 300 mg as a daily dose of the more stable acetylated form. Glutathione support is about steady daily intake over time.

When will I notice something?
Glutathione isn't a stimulant. Research on oral glutathione shows body stores build over weeks to months of consistent use.*

Can I take it with NAC, NMN or NAD+?
Many customers pair glutathione with other longevity supplements. Check with your healthcare provider if you take medications or have a medical condition.

What if it's not for me?
You're covered by our 60-day money-back guarantee on direct-site orders — even if opened, no return required. One refund per product per customer; shipping is non-refundable.

References

1. Fanelli S, Francioso A, Cavallaro RA, d'Erme M, Putignano P, Miraglia N, Mosca L. Oral administration of S-acetyl-glutathione: impact on the levels of glutathione in plasma and in erythrocytes of healthy volunteers. Int J Clin Nutr Diet. 2018;4:134. doi:10.15344/2456-8171/2018/134
2. Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015;54(2):251-263. doi:10.1007/s00394-014-0706-z
3. Sinha R, Sinha I, Calcagnotto A, et al. Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function. Eur J Clin Nutr. 2018.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.